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		<title>Almetuzamab: Promise in Multiple Sclerosis; UK Research</title>
		<link>http://medicaleducator.co.uk/almetuzamab-promise-in-multiple-sclerosis-uk-research.html</link>
		<comments>http://medicaleducator.co.uk/almetuzamab-promise-in-multiple-sclerosis-uk-research.html#comments</comments>
		<pubDate>Sat, 25 Oct 2008 12:37:21 +0000</pubDate>
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				<category><![CDATA[New Research]]></category>
		<category><![CDATA[almetuzamab]]></category>
		<category><![CDATA[MS]]></category>
		<category><![CDATA[multiple]]></category>
		<category><![CDATA[Research]]></category>
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		<description><![CDATA[Published this week in the New England Journal of Medicine, promising trial data for the new monoclonal antibody Almetuzamab.The conclusions of the study were as follows:
&#8220; In patients with early, relapsing–remitting multiple sclerosis, alemtuzumab was more effective than interferon beta-1a but was associated with autoimmunity, most seriously manifesting as immune thrombocytopenic purpura. The study was [...]]]></description>
			<content:encoded><![CDATA[<p>Published this week in the New England Journal of Medicine, promising trial data for the new monoclonal antibody Almetuzamab.The conclusions of the study were as follows:</p>
<p><em>&#8220;<span style="font-family: arial,helvetica;"> In patients with early, relapsing–remitting<sup> </sup>multiple sclerosis, alemtuzumab was more effective than interferon<sup> </sup>beta-1a but was associated with autoimmunity, most seriously<sup> </sup>manifesting as immune thrombocytopenic purpura. The study was<sup> </sup>not powered to identify uncommon adverse events.&#8221;</span></em></p>
<p>NEJM abstract link <a title="Alemtuzamab" href="http://content.nejm.org/cgi/content/short/359/17/1786" target="_blank">here</a></p>
<p>There has been extensive media coverage of the drug on UK media sources including coverage of patients who have received the drug. Cambridge researchers showed a reduction in relapse rate and disability in 334 patients suffering from multiple sclerosis for less than 3 years.</p>
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