Paracetamol “antidote”

Clinical Pharmacology and Toxicology

Which of the following is the “antidote” used in paracetamol?

  • N acetylcysteine
  • 5 amino Salicylate
  • Acetylcholinesterase
  • Pabrinex
  • Haemofiltration

N acetylcysteine.

Do not confuse N acetylcysteine (parvolex) with pabrinex.

Treatment is given over a set of quite complex infusion schedules over 24 hours. There is advice given on the calculation of doses in the BNF.